Oxidative Phosphorylation and Related Processes
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چکیده
منابع مشابه
The effect of thyroxine and related compounds on oxidative phosphorylation.
The finding that oxidative phosphorylation is uncoupled by nitroand halophenols (l-3) has led a number of investigators (4-10) to examine the effect of a physiological halophenol, thyroxine, on this process. Uncoupling of phosphorylation from respiration has been observed following addition of thyroxine and related compounds to suspensions of mitochondria (4-8) as well as in mitochondria isolat...
متن کاملRestoration by albumin of oxidative phosphorylation and related reactions.
Bovine serum albumin prevented the effects of pentachlorophenol, 2,4-dinitrophenol, and various other reagents upon oxidative phosphorylation, the orthophosphate-adenosine triphosphate exchange reaction, adenosine triphosphatase, and respiratory control of rat liver mitochondria. More significantly, albumin restored the capacity for oxidative phosphorylation and the ancillary reactions, includi...
متن کاملBarbiturates and oxidative phosphorylation.
It has been claimed that barbiturates uncouple oxidative phosphorylations (Brody & Bain, 1954; Brody, 1955). These authors have demonstrated that during the oxidation of pyruvate by liver and brain mitochondria, phosphate uptake was lowered proportionately more than oxygen uptake. Support for the uncoupling theory was derived from certain similarities between the barbiturates and 2:4dinitrophen...
متن کاملVitamin K and oxidative phosphorylation.
1. Oxidative phosphorylation was studied in a cell-free preparation of Mycobacterium phlei and in rat-liver mitochondria. Phosphorylation was destroyed in both systems by long-wave ultraviolet radiation and restored by the addition of small amounts of [2-Me-(14)C,(3)H]phylloquinone. When the radioactive quinones were recovered from the phosphorylating system and chromatographed with carrier phy...
متن کاملElectron Transport and Oxidative Phosphorylation
Objectives: I. Describe the structure of the Mitochondrion. A. Compare the structure of the outer membrane to the structure of the inner membrane. B. What metabolic pathways are localized to the mitochondrion? 1. Where in the mitochondrion are they located? II. What is(are) the overall chemical reaction(s) of electron transport and oxidative phosphorylation? III. Describe the overall makeup of ...
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ژورنال
عنوان ژورنال: Nature
سال: 1963
ISSN: 0028-0836,1476-4687
DOI: 10.1038/200221a0